We have basically been conditioned into believing that orgasms are healthy for you, which is in essence true, but how about too many orgasms? For example, is having an orgasm every minute for 24 hours unhealthy? Logically, too many orgasms would eventually lead to neurotransmitter deficiencies which would ultimately lead the human body into a state of withdrawal. Drugs can be used as the analogy in this case. Cocaine flushes the brain with dopamine. Long term use and then sudden discontinuous would leave the body in a state of shock (withdrawal) because dopamine levels plummet. Orgasms can be though as the same way. Orgasms are so pleasurable because of the dopamine and endorphin that flood your brain. So in theory, if someone were to have so many orgasms, then the brain would be depleted of these neurotransmitters and so you will experience withdrawal. I read a source a couple of days ago about how orgasms can possibly deplete neurotransmitter but I don’t remember where the source is. Oh well it makes sense… If this is true then essentially that is proof that drugs are much more pleasurable than sex lol. Think about it… Orgasm lasts a couple seconds and heroin lasts a couple hours! I remember an addict told me that heroin feels like 1000 orgasms! I believe him because I’ve done oxycodone and I would say it feels at least 10 times better than sex.
Hey Jennifer, great response! I’m definitely going to give you the best answer I’m just going to wait a bit longer to see if I get more answers. Hey if you don’t mind me asking, are you a sort of biologist?
Chosen Answer:
First off, dopamine is not exclusive to sex and pleasure. It’s responsible for reward-driven learning. When you do well on a test and see your high score you get a small boost of dopamine, and that sure as hell isn’t an orgasm 
Dopamine is only one of many neurotransmitters involved in orgasm. It’s a complex balance of chemistry that includes an increase of dopamine to motivate your sexual conduct, and a release of oxytocin during orgasm, as well as a down regulation of serotonin and prolactin. Under these ideal circumstances your brain then goes through sort of a “programmed” sequence of events in which certain parts of the brain are turned off (amygdala, hippocampus, ie. areas involved in alertness and anxiety), and blood flow to others increases (primary somatosensory cortex, nucleus accumbens; ie. areas responsible for pleasure and tactile sensation), all while a signal is sent through axons down to the base of your spine to stimulate motor neurons in your pudendal nerve, causing the rhythmic contractions of certain important muscles lol. Fun fact: More of the brain shuts down for a longer duration in a female orgasm
Dopamine is not “The” orgasm, it’s just one piece of the puzzle.
These neurotransmitters are not completely depleted unless you have a disorder such as Parkinson’s Disease (cell death in a center responsible for producing dopamine). There is a re-uptake mechanism that allows several of the neurotransmitters to be returned to their originating neuron between the synaptic cleft. New dopamine is also being manufactured on demand. That said, dopamine receptors can down-regulate. If there is a constant supply of dopamine being excreted, in an attempt to reach homeostasis under these new circumstances, less of these molecules will effectively bind.. So you will have the same (increased) amount of dopamine floating around, it just takes more to have the same effect. This is an important mechanism in addiction. As tolerance builds, it takes more and more of that drug to create a similar effect because these receptors are down-regulated. As with any tolerance, taking a break will eventually allow the receptors to return to their previous state.
From personal experience: 1. I’ve had oxycodone and it’s undoubtedly pleasurable but nothing compared to a series of intense multiple orgasms, and 2. I’ve never had orgasms nonstop for 24 hours, but I’ve had long lovemaking sessions and sometimes it’s my 10th orgasm that’s the most intense. Yes, some drugs mimic and can hijack the same reward system used for our sexual response, but, by introducing new chemicals that are not natural to our neurochemistry, new harmful neural pathways can be formed, and withdrawal symptoms occur when exogenous chemicals are discontinued. There’s nothing exogenous about an orgasm.
Sex addiction is certainly a problem for some, but it’s not exactly the same. Absent of heart disease and stroke orgasms are quite healthy and “can” be an important part of forming a bond with your partner. If you have “too many” of them your body is well equipped to get itself back to normal in due course, which is certainly not the case with heroin.
by: Jennifer
on: 4th February 13